NLRP3-IN-72 - CAS 3043952-13-9

NLRP3-IN-72 (Compound 2) is a benzimidazole derivative. It exhibits anti-inflammatory and antioxidant properties, with an IC50 of 0.3 μM for NLRP3 IL-1β, a PD50 of 0.4 μM for protection against cell pyroptosis, and an EC50 of 0.6 μM for inducing HO-1.

NOD-like Receptor (NLR), Pyroptosis, Interleukin, ROS

Apoptosis, Immunology/Inflammation

3043930

C19H20FN5O

353.393

FC=1C=CC2=C(N=C(NC3=NC=4C=C(C=CC4O3)CN(C)CC)N2C)C1

-20°C

Ice Packs

Small Compound