NLRP3-IN-82 - CAS 3091347-92-8

NLRP3-IN-82 (Compound 2b) is an NLRP3 inhibitor that significantly suppresses IL-1β release in HMDM cells with an IC50 of less than 5 nM. This compound is applicable for research into neurological disorders such as Alzheimer's disease, inflammatory conditions like inflammatory bowel disease, and metabolic disorders such as obesity.

NOD-like Receptor (NLR)

Immunology/Inflammation

3091247

C20H23ClN6O

398.89

CN1C[C@]2(N(C=3C=4N(C(=NN3)C5=C(O)C=C(Cl)C(C)=C5)C=CN4)CC[C@]2(CC1)[H])[H]

-20°C

Ice Packs

Small Compound