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Molfinity

NLRP3-IN-9 - CAS 88039-46-7

NLRP3-IN-9 - CAS 88039-46-7

MF-0093695-01

$36.16 USD
$36.16 USD
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Product Details

  • Bioactivity

    NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.

  • Target

    NOD, NOD-like Receptor (NLR)

  • Related Pathways

    Immunology/Inflammation, NF-κB

  • CAS Number

    87986

  • Purity

    0.9964

  • Molecular Formula

    C12H13ClO3

  • Molecular Weight

    240.68

  • SMILES

    CCOC(=O)C(=C)C(O)c1ccccc1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound