NMac1 - CAS 1332290-68-2

NMac1 (Nm23 activator 1) is a natural compound, cassumunene, derived from Zingiber cassumunar Roxb. and traditionally used as an anti-inflammatory agent in East Asia. NMac1 exhibits anti-metastatic potential by directly interacting with the C-terminal of Nm23-H1, activating its NDP kinase (NDPK) enzymatic activity in vitro. NMac1 inhibits breast cancer metastasis in vivo.

Ras, AMPK, Others, mTOR, ERK, OXPHOS, ROS

Apoptosis, MAPK, PI3K/Akt/mTOR signaling, Others, Chromatin/Epigenetic, Immunology/Inflammation

1332220

>99.99%

C24H28O4

380.48

C(=C/C1=CC(OC)=C(OC)C=C1)\C2C(C=CCC2)C3=CC(OC)=C(OC)C=C3

-20°C

Ice Packs

Natural Product