NMK-TD-100 - CAS 1252802-38-2

NMK-TD-100 is a microtubule modulating agent with anti-proliferative activity by disrupting microtubule functions through tubulin binding. NMK-TD-100 blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin. Polymerization of tissue purified tubulin into microtubules was inhibited by NMK-TD-100 with an IC50 value of 17.5±0.35 μM.

Apoptosis, Others, Microtubule Associated

Cytoskeletal Signaling, Apoptosis, Others

1252762

C19H17N3O3S

367.42

O(C)C=1C=C(C=2SC(C=3C=4C(NC3)=CC=CC4)=NN2)C=C(OC)C1OC

-20°C

Ice Packs

Small Compound