NMS-0963 - CAS 2765304-82-1

NMS-0963 (compound 1), an orally active inhibitor of spleen tyrosine kinase (SYK), demonstrates an IC50 value of 3 nM. Additionally, NMS-0963 effectively inhibits the proliferation of the BaF3-TEL/SYK cell line at 27 nM [1].

Syk

Tyrosine Kinase/Adaptors, Angiogenesis

2765304-82-1

C23H29N7O3

451.52

C(N[C@H](CN1CCC1)C)(=O)C2=CC(=NN2C)C3=NC(NC4=CC(OC)=CC(OC)=C4)=NC=C3

-20°C

Ice Packs

Small Compound