NNK - CAS 64091-91-4

NNK is a nitrosated derivative of nicotine that activates the ERK1/2 and PKCα signaling pathways, induces Bcl2 phosphorylation at Ser70, and activates c-Myc at Thr58 and Ser62, thereby promoting the proliferation and survival of human lung cancer cells, and is commonly used to establish lung cancer mouse models.

Lipoxygenase

Metabolism

63996

>99.99%

C10H13N3O2

207.23

CN(CCCC(=O)c1cccnc1)N=O

-20°C

Ice Packs

Small Compound