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NNRT-IN-10 - CAS 2459751-62-1

NNRT-IN-10 - CAS 2459751-62-1

SKU:MF-0117982-01

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  • Bioactivity

    NNRT-IN-10 is a potent, selective, and orally bioavailable non-nucleoside reverse transcriptase inhibitor (NNRTI) for HIV-1. The compound exhibits EC50 values ranging from 1.16 to 18.3 nM against HIV and its variants. NNRT-IN-10 has favorable pharmacokinetic properties and safety profile, making it suitable for research on AIDS caused by HIV-1.

  • Target

    HIV Protease, Cytochromes P450, Potassium Channel, Reverse Transcriptase

  • Related Pathways

    Metabolism, Proteases/Proteasome, Microbiology/Virology, Membrane transporter/Ion channel

  • CAS Number

    2459688

  • Molecular Formula

    C31H32N6O3S

  • Molecular Weight

    568.69

  • SMILES

    O(C=1C2=C(N=C(NC3CCN(CC4=CC=C(S(C)(=O)=O)C=C4)CC3)N1)N=CC=C2)C5=C(C)C=C(/C=C/C#N)C=C5C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound