NOD1-IN-1 - CAS 687627-78-7

NOD1/2-IN-1 (Compound 2) is a potent inhibitor of RIPK2 with an IC50 value of 0.65 nM as determined by the ADP-Glo assay. It selectively inhibits the NOD1 pathway, with an IC50 of 33 nM, effectively blocking the production of pro-inflammatory cytokines and thereby reducing inflammatory responses. This compound has potential applications in the research of colitis.

NOD-like Receptor (NLR)

Immunology/Inflammation

687542

C16H14ClN3O3

331.75

ClC1=CC=C(C=C1O)NC=2N=CN=C3C=C(OC)C(OC)=CC32

-20°C

Ice Packs

Small Compound