NOD2 antagonist 1 - CAS 2411441-54-6

NOD2 antagonist 1 (compound 32) is an effective and selective NOD2 antagonist (IC50: 5.23 μM) . In THP-1 cells, it represses Muramyl DiDP (MDP) -induced IL-8 secretion and, in PBMCs cells, inhibits MDP-induced elevation of IL-6, IL-10, and TNF-α.

NOD-like Receptor (NLR), Others

Immunology/Inflammation, Others

2411381

C26H26N4O3S

474.57

C(C(NC=1C=C2C(=CC1)CCC2)=O)N3C=4C(N=C3CCNS(=O)(=O)C5=CC=CC=C5)=CC=CC4

-20°C

Ice Packs

Small Compound