(+) -Norfenfluramine hydrochloride - CAS 37936-89-3

(+) -Norfenfluramine hydrochloride, a significant liver metabolite of (+) -fenfluramine, functions as a selective agonist for the 5-HT 2B receptor (K i: 11.2 nM), effectively stimulating inositol phosphate hydrolysis and elevating intracellular Ca2+. It is utilized in research focusing on primary pulmonary hypertension and valvular heart disease.

5-HT Receptor

Neuroscience, GPCR/G Protein

37844

C10H13ClF3N

239.67

Cl.C[C@H](N)Cc1cccc(c1)C(F)(F)F

-20°C

Ice Packs

Small Compound