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Molfinity

NOX2-IN-2 - CAS 2648709-79-7

NOX2-IN-2 - CAS 2648709-79-7

MF-0158938-01

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Product Details

  • Bioactivity

    NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (Ki) of 0.24 μM, and effectively suppressing reactive oxygen species (ROS) production from NOX2 in cellular contexts [1].

  • Target

    Others, NADPH

  • Related Pathways

    Others, Metabolism

  • CAS Number

    2648709-79-7

  • Molecular Formula

    C25H25N7O3

  • Molecular Weight

    471.51

  • SMILES

    N1=NN(C=C1COC=2C=CC3=NC(N)=CC=C3C2)CCOCCOC=4C=CC5=NC(N)=CC=C5C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound