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NOX2-IN-2 diTFA - CAS 2648709-80-0

NOX2-IN-2 diTFA - CAS 2648709-80-0

MF-0142629-01

$1,778.67 USD
$1,778.67 USD
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Product Details

  • Bioactivity

    NOX2-IN-2 diTFA (compound 33) is an effective inhibitor of NOX2, targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. This compound effectively suppresses the production of ROS generated by NOX2 in cells.

  • Target

    NADPH

  • Related Pathways

    Metabolism

  • CAS Number

    2648629

  • Molecular Formula

    C29H27F6N7O7

  • Molecular Weight

    699.56

  • SMILES

    O=C(C(F)(F)F)O.NC1=CC=C2C(C=CC(OCC3=CN(CCOCCOC4=CC5=CC=C(N)N=C5C=C4)N=N3)=C2)=N1.O=C(C(F)(F)F)O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound