NP10679 - CAS 2914889-88-4

NP10679 is an orally available, selective, brain-penetrating, potent, and pH-sensitive N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit.NP10679 inhibits histamine H1, hERG channels, and CYP enzymes, and may be useful in the study of epilepsy and ischemic stroke.

Cytochromes P450, Potassium Channel, Histamine Receptor, NMDAR

Metabolism, Neuroscience, GPCR/G Protein, Immunology/Inflammation, Membrane transporter/Ion channel

2914797

0.9943

C23H26F3N3O3

449.47

O(C[C@@H](CN1CCN(CC1)C2=CC=C(C(F)(F)F)C=C2)O)C=3C=C4C(=CC3)NC(=O)CC4

-20°C

Ice Packs

Small Compound