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Molfinity

NPBA - CAS 524033-40-7

NPBA - CAS 524033-40-7

MF-0119984-01

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Product Details

  • Bioactivity

    NPBA, a potassium K2P channel TASK-3 (KCNK9) agonist, concurrently functions as a blocker of the tandem pore domain weak inward rectifying K+ channel (TWIK2) . This compound effectively inhibits NLRP3 inflammasome activation in macrophages [1].

  • Target

    Others, Potassium Channel

  • Related Pathways

    Membrane transporter/Ion channel, Others

  • CAS Number

    524033-40-7

  • Molecular Formula

    C16H14F3N3O3

  • Molecular Weight

    353.3

  • SMILES

    N(CCNC(=O)C1=CC=CC=C1)C2=C(C(F)(F)F)C=C(N(=O)=O)C=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound