NPD-1335 - CAS 2376326-31-5

NPD1335, a potent inhibitor of Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1), exhibits submicromolar activity against T. brucei parasites and an improved cytotoxicity profile. By elevating intracellular cAMP levels, NPD1335 disrupts the cell cycle, leading to cell death [1].

Parasite, Others, PDE

Others, Metabolism, Microbiology/Virology

2376290

C28H29N3O3

455.55

[H][C@]12CC=CC[C@@]1([H])C(=NN(C(C)C)C2=O)c1ccc(OC)c(c1)C#CC(=O)NCc1ccccc1

-20°C

Ice Packs

Small Compound