NPD10084 - CAS 1040706-91-9

NPD10084 is an inhibitor of pyruvate kinase PKM2 that blocks non-glycolytic signaling in cancer cells by disrupting PKM2's interaction with β-catenin or STAT3, thus inhibiting downstream pathways. It demonstrates antiproliferative effects against colorectal cancer cells both in vitro and in vivo [1].

PKM

Metabolism

1040706-91-9

C21H19N3O2

345.39

C(=O)(N1CC=2C=3C(NC2CC1)=CC=CC3)C4=CC=5C(N4)=CC=CC5OC

-20°C

Ice Packs

Small Compound