NR-7h - CAS 2550399-06-7

NR-7h is a potent and selective degrader of p38α and p38β, exhibiting DC50 values of 24 nM for p38α in T47D cells and 27.2 nM in MB-MDA-231 cells, respectively [1].

Others, p38 MAPK, PROTACs

Others, MAPK, PROTAC

2550399-06-7

C48H50BrF2N9O8

998.87

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCCCNC(CCCN4C=C(CCCCNC(=O)C5=CC(=C(C)C=C5)N6C(=O)C(Br)=C(OCC7=C(F)C=C(F)C=C7)C=C6C)N=N4)=O

-20°C

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PROTAC