NR2F1 agonist 1 - CAS 374101-64-1

NR2F1 agonist 1, a specific nuclear receptor NR2F1 activator, initiates dormancy programs in cancer cells by upregulating NR2F1 and its target genes controlling dormancy. This compound promotes neural crest-like features and suppresses growth in head and neck squamous cell carcinoma (HNSCC) through NR2F1 activation. Moreover, NR2F1 agonist 1 demonstrates tumor growth inhibition in a mouse primary tumor model.

Others, Orphan Receptor

GPCR/G Protein, Others

374036

C28H30N4OS

470.63

CCSC1=NN=C2N1C1=C(C(=O)N2CCC2=CC=CC=C2)C2(CCCCC2)CC2=C1C=CC=C2

-20°C

Ice Packs

Small Compound