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Nrf2 activator 17 - CAS 3059044-55-9
Nrf2 activator 17 - CAS 3059044-55-9
SKU:MF-0110799-01
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Product Details
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Bioactivity
Nrf2 activator 17 (compound 10) is an Nrf2 agonist that inhibits the interaction between Keap1 and Nrf2 with an IC50 value of <0.1 pM. In HepG2 cells, it demonstrates an EC50 of <10 μM.
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Target
Nrf2, Serotonin Transporter
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Related Pathways
Immunology/Inflammation, Neuroscience
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CAS Number
3058980
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Molecular Formula
C29H35N5O4
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Molecular Weight
517.62
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SMILES
O=C(O)CC1C2=CC=C3C(=C2)CN(C(=O)N4CCC(OCCCCN5N=NC=6C5=CC=C1C6C)CC4)CC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound