Nrf2 degrader 1 - CAS 3025286-00-1

Nrf2 degrader 1 (compound 1), a PROTAC Nrf2 degrader, exhibits anticancer properties by inhibiting the growth of cancer cells. It demonstrates IC 50 values of 100 nM for A549 cells and 40 nM for LK-2 cells, indicating potent efficacy [1].

Nrf2, PROTACs

PROTAC, Immunology/Inflammation

3025286-00-1

C45H42N6O8S

826.92

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCOCCOC4=CC(CC(NC5=NC(=C(C)S5)C=6C=C7C(=CC6)N(C(=O)C8=C(C)C=CC=C8)CC7)=O)=CC=C4

-20°C

Ice Packs

PROTAC