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Nrf2-IN-3 - CAS 6325-13-9

Nrf2-IN-3 - CAS 6325-13-9

SKU:MF-0095432-01

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  • Bioactivity

    Nrf2-IN-3 is a mKEAP1-selective NRF2 inhibitor that selectively binds KEAP1 mutants and restores their NRF2 inhibitory function by repairing the disrupted KEAP1/NRF2 interaction, and selectively sensitizes cisplatin in xenografts of mouse mKEAP1 cancer cells.

  • Target

    Nrf2, ROS

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    6303

  • Purity

    0.9807

  • Molecular Formula

    C22H26N4O4S

  • Molecular Weight

    442.53

  • SMILES

    O=C(NN=CC=1C=CC=CC1O)CCCSCCCC(=O)NN=CC=2C=CC=CC2O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound