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Nrf2-IN-3 - CAS 6325-13-9
Nrf2-IN-3 - CAS 6325-13-9
SKU:MF-0095432-01
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$51.86 USD
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$51.86 USD
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Product Details
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Bioactivity
Nrf2-IN-3 is a mKEAP1-selective NRF2 inhibitor that selectively binds KEAP1 mutants and restores their NRF2 inhibitory function by repairing the disrupted KEAP1/NRF2 interaction, and selectively sensitizes cisplatin in xenografts of mouse mKEAP1 cancer cells.
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Target
Nrf2, ROS
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Related Pathways
Immunology/Inflammation
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CAS Number
6303
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Purity
0.9807
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Molecular Formula
C22H26N4O4S
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Molecular Weight
442.53
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SMILES
O=C(NN=CC=1C=CC=CC1O)CCCSCCCC(=O)NN=CC=2C=CC=CC2O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound