Nrf2-IN-4 - CAS 2417486-06-5

Nrf2-IN-4 is an Nrf2 inhibitor that induces ferroptosis by disrupting cellular iron homeostasis, promoting ferritin degradation, and ultimately triggering ferroptosis. It activates lysosomes through iron-dependent reactive oxygen species (ROS) production and lysosomal acidification. Nrf2-IN-4 demonstrates significant antitumor effects and is applicable in breast cancer research.

Nrf2, ROS, Ferroptosis, ATG

Immunology/Inflammation, Apoptosis, Autophagy

2417486-06-5

C20H13Cl2N5S

426.32

ClC=1C=CC(=CC1Cl)C=2N=C(SC2)NN=C(C3=NC=CC=C3)C4=NC=CC=C4

-20°C

Ice Packs

Small Compound