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Molfinity

NRX-252262 - CAS 2438637-61-5

NRX-252262 - CAS 2438637-61-5

SKU:MF-0094088-01

Regular price $119.25 USD
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  • Bioactivity

    NRX-252262 is a potent enhancer of the interaction between β-Catenin and its cognate E3 ligase, SCFβ-TrCP, inducing mutant β-Catenin degradation (EC50: 3.8 nM) .

  • Target

    Molecular Glues, E1/E2/E3 Enzyme, Wnt/beta-catenin

  • Related Pathways

    Cytoskeletal Signaling, PROTAC, Stem Cells, Ubiquitination

  • CAS Number

    2438571

  • Purity

    0.9987

  • Molecular Formula

    C23H17Cl2F3N2O4S

  • Molecular Weight

    545.36

  • SMILES

    COc1cc2CN(Cc2cc1OC)C(=O)c1c(Sc2c(Cl)cccc2Cl)cc([nH]c1=O)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC