Molfinity

NS 6740 - CAS 753499-14-8

SKU:MF-0152487

$1,045.96 USD

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Size 50 mg

Product Details

Bioactivity
High affinity α7 nAChR partial agonist (Ki = 1.1 nM in rat; Emax < 10% of the response to ACh in rat and human) . Inhibits ACh (IC50 = 2.7 nM) at α7 nAChR. Reduces LPS-induced TNF-α release from microglia enriched cultures. Anti-inflammatory.
Target
Others
Related Pathways
Others
CAS Number
753477
Molecular Formula
C19H20ClF3N2O2
Molecular Weight
400.83
SMILES
Cl.FC(F)(F)c1cccc(c1)-c1ccc(o1)C(=O)N1CCN2CCC1CC2 |TLB:16:18:22.23:25.26|
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound