NS5A-IN-4 - CAS 2088243-03-0

NS5A-IN-4 (Compound 1.12) is a pan-genotypic, orally active inhibitor of the hepatitis C virus (HCV) NS5A, with IC50 values of 1.2, 2296, 4.6, 362, 10.3, and 693 pM against genotypes gT1b, gT1a, gT2a, gT3a, gT4a, and gT5a, respectively [1].

HCV Protease, Others

Microbiology/Virology, Others, Proteases/Proteasome

2088243-03-0

C47H48N8O6

820.93

C([C@@H](NC(OC)=O)C(C)C)(=O)N1[C@@H](CCC1)C=2NC(=CN2)C3=CC(=C(C#CC#CC=4NC(=NC4)[C@H]5N(C([C@H](NC(OC)=O)C6=CC=CC=C6)=O)CCC5)C=C3)C7=CC=CC=C7

-20°C

Ice Packs

Small Compound