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Molfinity
NSC 288387 - CAS 61369-43-5
NSC 288387 - CAS 61369-43-5
SKU:MF-0156745-01
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Product Details
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Bioactivity
NSC 288387, a pan-flavivirus MTase inhibitor, binds to the SAM-binding pocket and effectively inhibits Zika virus (ZIKV) with an IC50 of 0.2 μM, also preventing viral replication in cell culture [1].
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Target
Virus Protease
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Related Pathways
Microbiology/Virology
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CAS Number
61321
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Molecular Formula
C19H16N4O3
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Molecular Weight
348.36
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SMILES
C(COC)N1C=2C(C(=O)N(C(=O)N2)C3=CC=CC=C3)=NC=4C1=CC=CC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound