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NSC 66811 - CAS 6964-62-1
NSC 66811 - CAS 6964-62-1
SKU:MF-0018447-01
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$38.41 USD
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$38.41 USD
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Product Details
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Bioactivity
NSC 66811is a novel inhibitor of the murine double minute 2 (MDM2) -p53 interaction. It binds to MDM2 with a Ki of 120 nM and activates p53 in cancer cells with a mechanism of action consistent with targeting the MDM2-p53 interaction.
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Target
Mdm2, MDM-2/p53
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Related Pathways
Apoptosis
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CAS Number
6901
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Purity
0.9694
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Molecular Formula
C23H20N2O
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Molecular Weight
340.42
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SMILES
Cc1ccc2ccc(C(Nc3ccccc3)c3ccccc3)c(O)c2n1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound