NSC-87877 disodium - CAS 56932-43-5

NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.

Phosphatase, Apoptosis

Metabolism, Apoptosis

56884

0.98

C19H13N3O7S2·2Na

503.42

[Na+].[Na+].Oc1c(cc(c2cccnc12)S([O-])(=O)=O)\N=N\c1ccc2cc(ccc2c1)S([O-])(=O)=O

-20°C

Ice Packs

Small Compound