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Molfinity

NSC145366 - CAS 1052515-37-3

NSC145366 - CAS 1052515-37-3

MF-0145697-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    NSC145366 is an inhibitor of Hsp90 activities which targets the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation. NSC145366 increases Hsp90 oligomerization resulting in allosteric inhibition of NTD ATPase activity (IC50=119μM) but does not compete with NTD or CTD-ATP binding.

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    1052475

  • Molecular Formula

    C37H63ClN2O4

  • Molecular Weight

    635.36

  • SMILES

    C(C)(C)(C1=CC=C(OCC(CNC(CC(C)(C)C)(C)C)O)C=C1)C2=CC=C(OCC(CNC(CC(C)(C)C)(C)C)O)C=C2.Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound