NSC177365 - CAS 80261-18-3

NSC177365 (NSC 1) is a CcrM inhibitor and acts as a competitive DNA inhibitor that disrupts DNA binding. It exhibits antibacterial activity with IC50 values of 2.3 μM against Caulobacter crescentus (C. crescentus) and 14.6 μM against M. lincolnii. Additionally, NSC177365 has the potential to reverse various neurodegenerative diseases and serves as an anticancer agent.

Antibacterial

Microbiology/Virology

80240

C23H23N7O4S

493.54

O=S(NC(C=C1)=CC=C1NC2=C3C=CC([N+]([O-])=O)=CC3=NC4=C2C=CC=C4)(CCCNC(N)=N)=O

-20°C

Ice Packs

Small Compound