NSC260594 - CAS 906718-66-9

NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-regulation of Wnt signaling proteins. Additionally, it can identify the G9-G10-A11-G12 RNA tetraloop of HIV, thereby obstructing the attachment of the Gag protein to the 5'-UTR. This compound demonstrates the potential to impede tumor proliferation and is utilized in the study of Triple-negative breast cancers (TNBCs) [1].

Others, Apoptosis, Bcl-2 Family, HIV Protease, Wnt/beta-catenin

Apoptosis, Proteases/Proteasome, Others, Microbiology/Virology, Cytoskeletal Signaling, Stem Cells

906643

C29H24N6O3

504.54

Cn1cc\c(cc1)=N\c1ccc(NC(=O)c2ccc(cc2)N=c2ccn(C)c3ccc(cc23)[N+]([O-])=O)cc1

-20°C

Ice Packs

Small Compound