NSC745885 - CAS 4219-52-7

NSC745885 is an antitumor agent non-toxic to normal cells that downregulates EZH2 via proteasome-mediated degradation. It exhibits toxicity against multiple normal and drug-resistant cancer cell lines and may be used in studies of advanced bladder cancer and oral squamous cell carcinoma.

Histone Methyltransferase, Apoptosis

Chromatin/Epigenetic, Apoptosis

4160

C14H6N2O2S

266.27

O=C1C=2C=CC=CC2C(=O)C=3C4=NSN=C4C=CC13

-20°C

Ice Packs

Small Compound