NSD2-IN-1 - CAS 2797183-37-8

NSD2-IN-1 (compound 38) is a potent and highly selective inhibitor of NSD2-PWWP1 (nuclear receptor-binding SET domain 2-PWWP1), with an IC50 value of 0.11 μM. By binding to NSD2-PWWP1, NSD2-IN-1 influences gene expression regulated by NSD2, resulting in apoptosis and cell cycle arrest [1].

Others, Apoptosis

Apoptosis, Others

2797138

C29H31N5

449.59

CN1C(=C(N=C1)C2=C(C)C=C(CN3CCC(N)CC3)C=C2C)C=4C5=C(C(C#N)=CC4)C=CC=C5

-20°C

Ice Packs

Small Compound