NTU281 - CAS 815619-12-6

NTU281 is a potent inhibitor of transglutaminase-2 that reduces the elevation of serum creatinine and proteinuria in diabetic rats and decreases glomerular type I collagen accumulation, Hic-5 and α-SMA expression, as well as apoptosis, and can be used in studies of diabetes-induced glomerulosclerosis.

Others, Glutaminase, Apoptosis

Proteases/Proteasome, Others, Apoptosis

815601

C25H31N2O6S

487.59

[C@H](CC1=CC=CC=C1)(C(N[C@@H](CCC(C[S+](C)C)=O)C(O)=O)=O)NC(OCC2=CC=CC=C2)=O

-20°C

Ice Packs

Small Compound