NU1085 - CAS 188106-83-4

NU1085 is a potent poly (ADP-ribose) polymerase (PARP) inhibitors have been developed that potentiate the cytotoxicity of ionizing radiation and anticancer drugs. The biological effects of NU1085 [Ki = 6 nM], in combination with temozolomide (TM) or topotecan (TP) have been studied in 12 human tumor cell lines (lung, colon, ovary, and breast cancer) . Cells were treated with increasing concentrations of TM or TP +/- NU1085 (10 microM) for 72 h.

Others

Others

188019

C14H11N3O2

253.26

NC(=O)c1cccc2nc([nH]c12)-c1ccc(O)cc1

-20°C

Ice Packs

Small Compound