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NU5455 - CAS 1257235-99-6
NU5455 - CAS 1257235-99-6
SKU:MF-0138173-01
Regular price
$1,383.80 USD
Regular price
Sale price
$1,383.80 USD
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Product Details
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Bioactivity
NU5455 is a selective, potent, orally active inhibitor of DNA-PKcs. It enhances the efficacy of locally released doxorubicin in liver tumor xenografts without causing adverse effects and also enhances the efficacy and toxicity of parenterally administered topoisomerase inhibitors.
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Target
Others, DNA-PK
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Related Pathways
Others, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair
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CAS Number
1257130
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Molecular Formula
C34H33N3O5S
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Molecular Weight
595.71
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SMILES
N(C(CN1CCOCC1)=O)(C)C=2C=C3C=4C(=C(C=CC4)C5=C6C(C(=O)C=C(O6)N7CC8OC(C7)CC8)=CC=C5)SC3=CC2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound