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Molfinity

NU5455 - CAS 1257235-99-6

NU5455 - CAS 1257235-99-6

SKU:MF-0138173-01

Regular price $1,383.80 USD
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  • Bioactivity

    NU5455 is a selective, potent, orally active inhibitor of DNA-PKcs. It enhances the efficacy of locally released doxorubicin in liver tumor xenografts without causing adverse effects and also enhances the efficacy and toxicity of parenterally administered topoisomerase inhibitors.

  • Target

    Others, DNA-PK

  • Related Pathways

    Others, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair

  • CAS Number

    1257130

  • Molecular Formula

    C34H33N3O5S

  • Molecular Weight

    595.71

  • SMILES

    N(C(CN1CCOCC1)=O)(C)C=2C=C3C=4C(=C(C=CC4)C5=C6C(C(=O)C=C(O6)N7CC8OC(C7)CC8)=CC=C5)SC3=CC2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound