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Molfinity

NU6140 - CAS 444723-13-1

NU6140 - CAS 444723-13-1

MF-0033671-01

$36.16 USD
$36.16 USD
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Product Details

  • Bioactivity

    NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM) . It shows 10- to 36-fold selectivity over other CDKs. NU6140 also effectively inhibits Aurora A and Aurora B (IC50s: 67 and 35 nM, respectively) . It also enhances the apoptotic effect and has anti-cancer activity.

  • Target

    CDK, Aurora Kinase

  • Related Pathways

    Chromatin/Epigenetic, Cell Cycle/Checkpoint

  • CAS Number

    444709

  • Purity

    0.9833

  • Molecular Formula

    C23H30N6O2

  • Molecular Weight

    422.52

  • SMILES

    CCN(CC)C(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound