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Nurr1 agonist 2 - CAS 742058-34-0

Nurr1 agonist 2 - CAS 742058-34-0

MF-0099443-01

$96.50 USD
$96.50 USD
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Product Details

  • Bioactivity

    Nurr1 agonist 2 is a Nurr1 agonist with an EC50 value of 0.07 μM. Nurr1 agonist 2 increases the mRNA expression of the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2) . Nurr1 agonist 2 binds to the recombinant Nurr1 ligand-binding domain (LBD) with a Kd of 0.14 μM. Nurr1 agonist 2 can be used to study parkinsonism.

  • Target

    NR4A, Others

  • Related Pathways

    Others, Endocrinology/Hormones

  • CAS Number

    742024

  • Purity

    0.9878

  • Molecular Formula

    C18H14O3S

  • Molecular Weight

    310.37

  • SMILES

    C(O)(=O)C=1SC(=CC1)C2=CC=C(OCC3=CC=CC=C3)C=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound