Nurr1 inverse agonist-1 - CAS 2758673-07-1

Nurr1 inverse agonist-1 is a indole-based inverse agonist targeting the neuroprotective transcription factor Nurr1, which plays a pivotal role in dopaminergic neuron regulation. Nurr1 inverse agonist-1 decreases the receptor's intrinsic transcriptional activity by up to more than 90% and revealed preference for inhibiting Nurr1 monomer activity. Nurr1 inverse agonist-1 enables the mechanistic study of Nurr1-mediated gene repression and the exploration of its potential implications in neurodegenerative disorders such as Parkinson’s disease.

Others

Others

2758673-07-1

C16H14N2O2

266.29

O=C(OC)C1=CN(C2=CC=C(C=C12)C=3C=NC=CC3)C

-20°C

Ice Packs

Small Compound