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NV03 - CAS 2448341-58-8
NV03 - CAS 2448341-58-8
SKU:MF-0023109-01
Regular price
$194.79 USD
Regular price
$107.25 USD
Sale price
$194.79 USD
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Product Details
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Bioactivity
NV03 is a selective antagonist of the UHRF1-H3K9me3 interaction (Kd=2.4 μM), binding to the UHRF1 tandem Tudor domain (TTD) to form a complex. It is suitable for cancer research. NV03 also functions as a ligand for E3 ligases in PROTAC synthesis.
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Target
Histone Methyltransferase, E1/E2/E3 Enzyme, Ligand for E3 Ligase
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Related Pathways
PROTAC, Chromatin/Epigenetic, Ubiquitination
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CAS Number
2448341-58-8
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Purity
0.9988
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Molecular Formula
C19H27N5O2S
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Molecular Weight
389.52
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SMILES
CCN(CC)CCCNC(=O)Cn1nc(C)n2c3ccsc3c(C)c2c1=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC