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Molfinity

NVP-2 - CAS 1263373-43-8

NVP-2 - CAS 1263373-43-8

MF-0018166-01

$47.38 USD
$47.38 USD
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Product Details

  • Bioactivity

    NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9/CycT activity (IC50: 0.514 nM) . NVP-2 shows inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases (IC50: 0.584 μM, 0.706 μM, and 0.605 μM, respectively) .

  • Target

    Apoptosis, CDK

  • Related Pathways

    Apoptosis, Cell Cycle/Checkpoint

  • CAS Number

    1263322

  • Purity

    0.9976

  • Molecular Formula

    C27H37ClN6O2

  • Molecular Weight

    513.07

  • SMILES

    COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound