Molfinity

NVP-ADW742 - CAS 475488-23-4

SKU:MF-0014859-01

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Size 1 mg 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg 50 mg

Product Details

Bioactivity
NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
Target
Apoptosis, IGF-1R
Related Pathways
Tyrosine Kinase/Adaptors, Apoptosis
CAS Number
475461
Purity
0.9979
Molecular Formula
C28H31N5O
Molecular Weight
453.58
SMILES
Nc1ncnc2n(cc(-c3cccc(OCc4ccccc4)c3)c12)C1CC(CN2CCCC2)C1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound