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Molfinity

NVP-BHG712 - CAS 940310-85-0

NVP-BHG712 - CAS 940310-85-0

MF-0094528-01

$32.42 USD
$32.42 USD
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Product Details

  • Bioactivity

    NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.

  • Target

    Ephrin Receptor, Raf, Src, Bcr-Abl

  • Related Pathways

    Angiogenesis, MAPK, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling

  • CAS Number

    940225

  • Purity

    0.9863

  • Molecular Formula

    C26H20F3N7O

  • Molecular Weight

    503.48

  • SMILES

    Cc1ccc(cc1Nc1nc(nc2n(C)ncc12)-c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound