NVP DPP 728 dihydrochloride - CAS 247016-69-9

NVP-DPP728 is a potent, reversible, nitrile-dependent inhibitor of dipeptidyl peptidase IV (DPP-IV) with an inhibition constant (K i) of 11 nM for human DPP-IV amidolytic activity. By inhibiting the degradation of glucagon-like peptide-1 (GLP-1), NVP-DPP728 enhances insulin release following glucose intake, making it useful for diabetes research [1].

Others, Proteasome

Ubiquitination, Proteases/Proteasome, Others

246938

C15H18N6O

298.34

C(CNCCNC1=CC=C(C#N)C=N1)(=O)N2[C@H](C#N)CCC2

-20°C

Ice Packs

Small Compound