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Molfinity

NVP-TAE 226 - CAS 761437-28-9

NVP-TAE 226 - CAS 761437-28-9

MF-0093646-01

$40.65 USD
$40.65 USD
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Product Details

  • Bioactivity

    NVP-TAE 226 (TAE226) is a potent FAK inhibitor (IC50: 5.5 nM), exhibiting even greater efficacy against Pyk2 (IC50: 3.5 nM), and is 10- to 100-fold less effective against IGF-1R, InsR, c-Met, and ALK.

  • Target

    Apoptosis, PYK2, FAK, c-Met/HGFR, IGF-1R

  • Related Pathways

    Apoptosis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Angiogenesis

  • CAS Number

    761400

  • Purity

    0.9917

  • Molecular Formula

    C23H25ClN6O3

  • Molecular Weight

    468.94

  • SMILES

    CNC(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)ncc1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound