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NVS-STG2 - CAS 3030588-01-0
NVS-STG2 - CAS 3030588-01-0
SKU:MF-0147841-01
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Product Details
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Bioactivity
NVS-STG2 is a STING agonist that promotes the oligomerization of human STING by binding to the pockets between adjacent STING dimer transmembrane domains, effectively acting as molecular glue. It triggers strong STING-mediated immune responses in cells and demonstrates antitumor activity in hSTING knock-in mice.
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CAS Number
3030588-01-0
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Molecular Formula
C25H33NO5
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Molecular Weight
427.54
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SMILES
O=C(O)C1=CC=C(NCC2=CC=C(C=C2)C3(OCC(C)(C)CO3)C(C)(C)C)C(OC)=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound