O-2545 hydrochloride - CAS 874745-43-4

O-2545 is a potent water-soluble central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor agonist with Ki values of 1.5 and 0.32 nM, respectively. Typically, cannabinoid agonists are highly lipophilic and require solubilization through surfactant agents or binding to water miscible substances like albumin, Tween 80, or Emulphor for use. When dissolved in saline, O-2545 has shown high efficacy in mouse behavioral models, administered either intravenously or intracerebroventricularly.

Others, Cannabinoid Receptor

Others, GPCR/G Protein

874745-43-4

C26H36N2O2?HCl

445

OC1=C2[C@]3([C@](C(C)(C)OC2=CC(C(CCCCN4C=CN=C4)(C)C)=C1)(CC=C(C)C3)[H])[H].Cl

-20°C

Ice Packs

Small Compound