O-Carboranylphenoxyacetanilide - CAS 2260545-92-2

O-Carboranylphenoxyacetanilide is an HIF-1α inhibitor that suppresses the activation of HIF-1α. It inhibits the transcriptional activity of HIF in HeLa cells (IC50: 0.74 μM) and also suppresses the molecular chaperone activity of HSP60 as well as the HSP60 ATPase activity.

HIF/HIF Prolyl-Hydroxylase, HSP

Chromatin/Epigenetic, Cytoskeletal Signaling, Metabolism

2260545-92-2

C16H24B11NO5

429.29

O=C(NC1=CC(=CC=C1O)B(O)O)COC2=CC=C(C=C2)C3456[BH]789[BH]%10%11%12[BH]%13%149[BH]%10%15%16[BH]%11%17%18[BH]%1276[BH]%17%195[BH]%20%214[BH]%13%15([BH]%148%203)[CH]%16%18%19%21

-20°C

Ice Packs

Small Compound