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O-Desmethyl Brinzolamide hydrochloride - CAS 2967475-56-3
O-Desmethyl Brinzolamide hydrochloride - CAS 2967475-56-3
SKU:MF-0121075-01
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Product Details
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Bioactivity
O-Desmethyl Brinzolamide hydrochloride (compound 6a), a potent metabolite derived from Brinzolamide, serves as a carbonic anhydrase (CA) inhibitor. It exhibits a dissociation constant (Kd) of 0.136 nM for CA II and an inhibitory concentration (IC50) of 165 nM for CA IV [1].
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Target
Carbonic Anhydrase, Drug Metabolite
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Related Pathways
Metabolism
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CAS Number
2967475-56-3
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Molecular Formula
C11H20ClN3O5S3
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Molecular Weight
405.94
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SMILES
O=S1(=O)C2=C([C@@H](NCC)CN1CCCO)C=C(S(N)(=O)=O)S2.Cl
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound